Cytotoxic Scalarane Sesterterpenes from the Sponge Hyrtios erectus
نویسندگان
چکیده
منابع مشابه
Antiproliferative Scalarane-Based Metabolites from the Red Sea Sponge Hyrtios erectus
Two new sesterterpenes analogs, namely, 12-acetoxy,16-epi-hyrtiolide (1) and 12β-acetoxy,16β-methoxy,20α-hydroxy-17-scalaren-19,20-olide (2), containing a scalarane-based framework along with seven previously reported scalarane-type sesterterpenes (3-9) have been isolated from the sponge Hyrtios erectus (order Dictyoceratida) collected from the Red Sea, Egypt. The structures of the isolated com...
متن کاملA New Bioactive Metabolite Isolated from the Red Sea Marine Sponge Hyrtios erectus.
Chemical investigation of the lipophilic fraction of Hyrtios erectus, a Red Sea sponge, yielded a new pentacyclic nitrogen-containing scalarane; 24-methoxypetrosaspongia C (1), together with the previously reported scalaranes sesterstatin 3 (2), 12-deacetyl-12-epi-scalaradial (3) and 12-deacetyl-12,18-di-epi-scalaradial (4). The compounds were identified using HRESIMS, 1D and 2D NMR experiments...
متن کاملBiologically Active Sesterterpenes from a New Caledonian
Chemical investigations of marine sponges from the genus Hyrtios has yielded a predominance of scalarane-type sesterterpenes.' We have previously isolated heteronemin and the new 12-epi-heteronemin as representatives of this class of sesterterpenes, from the marine sponge Hyrtìos erecta collected in New Caledonia? However, both scalarane-type sesterterpenes and those of the manoalide family hav...
متن کاملBioactive Natural Products of Marine Sponges from the Genus Hyrtios.
Marine sponges are known as a rich source for novel bioactive compounds with valuable pharmacological potential. One of the most predominant sponge genera is Hyrtios, reported to have various species such as Hyrtios erectus, Hyrtios reticulatus, Hyrtios gumminae, Hyrtios communis, and Hyrtios tubulatus and a number of undescribed species. Members of the genus Hyrtios are a rich source of natura...
متن کاملCytotoxic scalarane sesterterpenoids from the South China Sea sponge Carteriospongia foliascens.
Eleven new scalarane sesterterpenoids, including three 20,24-bishomo-25-norscalaranes, carteriofenones A–C (1–3), and eight 20,24-bishomoscalaranes, carteriofenones D–K (4–11), along with two known analogues (12 and 13), were obtained from the marine sponge Carteriospongia foliascens collected from the South China Sea. Their planar structures and relative configurations were elucidated by exten...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Marine Drugs
سال: 2020
ISSN: 1660-3397
DOI: 10.3390/md18050253